they transitioned the astrocytes to a pathogenic state by adding microglia-derived cytokines, which are the molecular cues that induce reactivity in neurodegenerative diseases. 2 Using this system to ...

Alongside microglia, astrocytes play a pivotal role in supporting brain functions, including metabolism, neurotransmitter ...

Astrocytes are star-shaped glial cells in ... "With our colleagues at AbbVie Inc, we also studied progression of microglia, endothelial, and neuronal cells in AD," added Das.

Using a single-cell sequencing technique, Brazilian researchers have created the first cell atlas of focal cortical dysplasia ...

Brain support cells called astrocytes have long been found around glioblastomas, leading scientists to think that the cells rally to help fight the tumors, but recent studies have found that the cells ...

We use induced pluripotent stem cells (iPSCs) representing neurological and psychiatric diseases. Differentiation of iPSCs into neurons, astrocytes, microglia allow us to analyze aberrant gene and ...

Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...

Differentiation of iPSCs into neurons, astrocytes and microglia allow us to analyze aberrant gene and protein expression, function and metabolism in developing and maturing human brain well before the ...

Xenon is one of the six noble gases. Its name derives from the Greek word for “strange”. In medicine, it has been used as an anaesthetic since the early 1950s and, more recently, to treat brain ...

Over the last decade, Dr. Fossati’s lab has developed robust and efficient protocols to generate human oligodendrocytes, astrocytes, microglia, neurons and complex 3D organoid cultures with the full ...