Mitochondria and mitochondrial autophagy play a vital role in cellular health and failure of these pathways can have a devastating effect on cellular homeostasis.

A report published in PLoS Biology provides evidence that PTEN-induced putative kinase 1 (PINK1) is involved in selective autophagy of dysfunctional mitochondria. Recessive mutations in the PINK1 ...

"Our findings are important because of this link between processes. Both mitochondria and autophagy are involved in metabolism, so it makes sense that they're connected. Researchers in cellular ...

More information: Isabel Gordaliza-Alaguero et al, Endogenous interactomes of MFN1 and MFN2 provide novel insights into interorganelle communication and autophagy, Autophagy (2024). DOI: 10.1080 ...

Scientists created a stem cell-based method to produce high-quality mitochondria at scale, enabling effective treatments for ...

Scientists have unveiled a revolutionary method for mass-producing high-quality human mitochondria, potentially transforming ...

View Full Profile. Learn about our Editorial Policies. B.H. Abuaita et al., “Mitochondria-derived vesicles deliver antimicrobial reactive oxygen species to control phagosome-localized Staphylococcus ...