Researchers use HAT (hypoxanthine-aminopterin-thymidine) medium to allow the selective proliferation of immortal monoclonal antibody-producing cell lines. The aminopterin in the HAT medium stops ...

In contrast, after adding 20 mg/kg of monoclonal antibody against CD40 ligand to the regimen on days 0 and 2, we observed four thromboembolic complications in nine recipients. These included two ...

Although the history of ADC development spans decades, recent clinical successes — along with advances in antibody engineering, chemical synthesis ... tethered to a monoclonal antibody.

‘Mono’ means one and 'clone' means identical copy. Monoclonal antibodies are, therefore, identical copies of one type of antibody. Antibodies bind to specific antigens on pathogens. This means ...

Antibodies that interfere with IL-6 function Tocilizumab is a monoclonal antibody directed against the IL-6 receptor that has established benefit in RA both with regards to clinical efficacy and ...