Myeloid lineage cells, including macrophages, dendritic cells, osteoclasts and precursor cells, all produce VEGF-C in response to inflammatory cytokines, which is mediated by the canonical NF-κB ...
The TREM2 receptor may hold the keys to understanding how myeloid cells affect immune responses to neurological disorders and cancer. Triggering receptors expressed on myeloid cells (TREMs) are a cell ...
A research team made a pivotal discovery in the field of cancer immunotherapy. The team identified a specific population of immune cells that play a critical role in successful treatment of relapsed ...
In a paper published in Science Bulletin, a Chinese team of scientists reported a comprehensive proteogenomic analysis of 101 Chinese AML patients, including proteomic and phosphoproteomic analyses ...
Ltd. have published findings from their work aiming to identify antigens that could represent novel targets for CAR T-cell therapies against acute myeloid leukemia (AML).
KAT2A is a histone acetyltransferase that functions as a transcriptional activator which, together with its paralogue KAT2B, is markedly overexpressed in acute myeloid leukemia (AML) compared to in ...