Cytovia Therapeutics is uniquely positioned to deliver on the therapeutic promise through its plug-and-play cell therapy platform and complementary bispecific NK cell engagers. NK cells readily ...
Unlike mature IL-18, this short form does not exit the cell but enters the nucleus, where it promotes the phosphorylation of STAT1 and ISG15 secretion, which in turn enhances NK cell anti-tumor ...
Hepatocellular carcinoma (HCC), the most common type of primary liver cancer, accounts for about 75–85% of all liver cancer ...
Cell division is the process of a cell splitting into two genetically identical daughter cells. The actin protein seen in this video is essential for successful cell division. While actin has several ...
One of the lead candidates in Sanofi natural killer (NK) cell engager alliance with Innate Pharma has shown encouraging and durable efficacy in various haematological cancers, according to a phase ...
Gilead Sciences' cell therapy Kite Pharma has bulked up its position in natural killer (NK) cell therapies, pledging up to $2.3 billion for a partnership with Shoreline Bioscience focusing on off ...
Biomissile Pharmaceuticals Co. Ltd. is developing multispecific antibodies that overcome resistance associated with antibody-drug conjugates via its next-generation natural killer (NK) cell engagers. ...
NK cells recognize cell-bound antibodies via CD16A (FcγRIIIA) to mediate antibody-dependent cellular cytotoxicity (ADCC). Potentiating therapeutic mAb-mediated CD16 activation of NK cells is an ...
A number of signalling pathways have been identified as crucial in controlling NK cell metabolic and functional responses. Interestingly, the levels of nutrients and metabolites within the immune ...