"Nerve cells die in the context of Alzheimer's disease as a consequence of a well-defined sequence of biochemical reactions, called 'necroptosis,'" explains Balusu, postdoctoral researcher in the ...

Host cells activate cell death pathways in response to bacterial manipulation of innate immune signalling, but the molecular ...

A study has uncovered that iron orchestrates the activation of two damaging cell death pathways—ferroptosis and ...

Necroptosis is a form of programmed necrosis. Necroptotic stimuli promote the interaction of the RIP1 and RIP3 kinases under conditions in which caspase-8 is not active. This RIP1/RIP3 complex ...