Scientists have created the most detailed wiring diagram of a mammalian brain to date, mapping every cell and synapse in a ...

The synaptic cleft in an electrical synapse is much smaller ... which involve rapid changes in voltage across their membrane. When a neuron’s dendrite or cell body receives enough inputs from other ...

Between the axon of a transmitting neuron and the dendrite of a receiving neuron is a gap called the synapse—the site at which signals are passed between the brain cells. The nervous system ...

Synaptic transmission is the biological process by which a neuron communicates with a target cell across a synapse. Chemical synaptic transmission involves the release of a neurotransmitter from ...

Our research investigates how these liquid-like properties contribute to the main function of the neuron in synaptic ...

There are two types of removal: Re-uptake – the neurotransmitter is reabsorbed back into the presynaptic neuron and restored inside a vesicle ready to be used again. For example, noradrenaline.

In order to become a distinct cell type like a muscle cell or a neuron, cells must go through a series of developmental steps, each closer to the final cell type. When cells reach the final step, they ...

Researchers devised a process to convert a skin cell directly into a neuron, eliminating the need to generate induced pluripotent stem cells. Such neurons could be used to treat spinal cord ...

“So, we’re using direct conversion, where instead of going through an iPSC intermediate, we’re going directly from a somatic cell to a motor neuron.” The original process involved a set of ...