The results of recent experiments implicate this signalling pathway in many stages of heart development, and provide mechanistic insight into the vital functions of Notch in the aetiology of ...

it could be suggested that tumour progression might select for cells that are refractive to Notch signalling in tissues in which absence of this pathway promotes growth, enhances survival and/or ...

A cell signaling mechanism of fundamental importance to animal development is the Notch pathway (Figure 1). It may be safely said that Notch signaling is required, in some reasonably direct fashion, ...