Scientists have tapped into the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision ...

The Summit supercomputer revealed how damaged strands of DNA are surgically repaired by a molecular pathway called nucleotide excision repair, or NER. NER’s protein components can change shape ...

it coordinates potentially dangerous steps in the base excision repair pathway. Figure 1: Schematic representation of single-nucleotide BER and alternatives for aborted intermediates. Recent ...