This way DNA can reproduce itself without changing its structure -- except for occasional errors, or mutations. The structure so perfectly fit the experimental data that it was almost immediately ...

DNA is the molecule that holds the instructions for all living things. DNA achieves this feat of storing, coding and transferring biological information though its unique structure. Replication of ...

These changes occur because the genome changes. The discovery of the structure of DNA together with an increasing understanding the part it plays in inheritance has proved that Alfred Russel ...

To preserve genome integrity and proper cell-cycle progression, eukaryotic cells have developed checkpoint functions that are constantly monitoring DNA integrity and that serve to coordinate ...

Chances are you've seen an illustration of DNA's double-helix structure and even pictures of the chromosomes that make up the human genome. But where and how does the famous double helix fit into ...

DNA is a complex molecule that consists of two strands coiled around each other to form a double helix structure. Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding ...

Describe the general organization, possible function, and frequency of genes and non-gene DNA sequences in a typical eukaryotic genome. Explain the functional significance of packaging ... Explain why ...

The size of the exonuclease III footprint of ligase bound to a single nick in duplex DNA is 19 to 21 nucleotides. The footprint is asymmetric, extending 8 to 9 nucleotides on the 3’-OH side of the ...

This odd arrangement, the authors found, influences the three-dimensional structure of the entire chromosome. “This is definitely a breakthrough within the field. We’ve been generating assemblies for ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

Varshavsky studied chromatin structure and wanted to develop new methods to detect the DNA-protein interplay in intact cells. Motivated to better understand chromatin structural organization, ...