Primary biliary cholangitis (PBC), also known as primary biliary cirrhosis, is a chronic and progressive disease that damages and can eventually destroy the bile ducts of the liver. Researchers ...

Sclerosing cholangitis and primary biliary cirrhosis, which is now called primary biliary cholangitis (PBC), are chronic cholestatic liver diseases, but they differ in their causes, affected bile ...

There isn’t a cure for PBC, but the right treatment plan can slow its progress and boost your quality of life as you live with it.

PBC is a chronic, autoimmune disease in which ... with its prevalence on the rise. Symptoms include debilitating fatigue and itching (pruritus), and it can worsen over time if not effectively ...

People with PBC often have increased levels of ALP in their blood. This can be an early sign of the disease before they develop noticeable symptoms of liver problems. It isn’t known yet whether ...

However, research on quality-of-life outcomes in patients with PBC suggests that effectively managing the condition requires more than simply watching lab values. Studies have shown that symptoms ...

PBC is more common in women and causes liver damage that can progress to liver failure, particularly if left untreated. The most common symptoms of PBC are pruritus (chronic itch) and fatigue ...

one of the most debilitating symptoms of PBC – with the PPAR delta agonist. The results are good news for Gilead, which acquired seladelpar as part of its $4.3 billion takeover of CymaBay ...