“Products created during setup decrease the efficiency of PCR,” says Joseph Donnenhoffer of Roche. The company's FastStart Taq polymerase has a one-base deletion that renders the enzyme ...

Quantitative PCR (qPCR) has been a gold standard in diagnostics, most recently demonstrated during the COVID-19 pandemic. Enzymes play a critical role in qPCR assays, largely by amplifying DNA ...

This method facilitates sequencing multiple regions of interest at the same time. Several components are involved in a PCR including template DNA, forward and reverse primers, DNA polymerase enzyme, ...

From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved dramatically. The discovery of ...

The PCR method, by enabling such amplification ... then the temperature is lowered so that an enzyme can copy the strand before it closes again, and the cycle is repeated. While most common ...

Use precise geolocation data and actively scan device characteristics for identification. This is done to store and access ...

Since PCR's advent, scientists have developed filters to manage predictable stutter ... they analyzed amino acid sequences to identify mutations that enhanced the polymerase’s binding to its template ...