X denotes truncating mutation. PEST2 domain 345–377; UBA domain 387–436. *Two different mutations reported to cause this truncation. ‡ Results from splice site mutations (intron 7 ...

The disease seems to occur in one of two patterns ... right infraorbital fissure, right maxillary bone, lacrimal bone, malar process and zygomatic bone. These bones were soft, suggesting that ...

Alendronate sodium is a bisphosphonate used to treat Paget disease of bone (PDB). The approved dosage ... by 73% and 72% in the tablet and OBS treatment groups, respectively.

In the course of evaluating the optimal duration of bisphosphonate treatment the FDA found ... drugs that are used only to treat Paget's disease or malignancy-associated hypercalcemia (DIDRONEL ...

The treatment of Paget's disease is surgery to remove the affected area of skin. Because the cancer may extend into what appears to be normal skin, a wide margin of tissue may be removed. Biopsies may ...

This, unfortunately, leads to late diagnosis when treatment options are significantly limited. How can we recognise this ...

New research suggests immune cell-derived exosomes may halt bone loss and ease joint pain in osteonecrosis, offering a ...