Hence, understanding the role of a given molecule or pathway in immune system function ... on a high-throughput scale (serial analysis of gene expression) or have yet to be proven reliable for ...

Research team developed PathActMarker, a software package for pathway activity inference and analysis. It preprocesses gene ...

The process of complex diseases is closely related to the dysregulation of key biological pathways, it is crucial to identify the dysfunctional ...

The study is useful for advancing spatial transcriptomics through its novel regression-based linear model (glmSMA) that integrates single-cell RNA-seq with spatial reference atlases, though its ...

Chickens treated to inhibit the sonic hedgehog (Shh) pathway during development grow feathers that resemble ancient ...

Single-cell RNA sequencing (scRNA-seq) was performed to analyze cell population characteristics and pathological gene expression patterns ... The type I IFN signaling pathway was found to be ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional elongation enzymes during gene expression, findings that may inform the ...

The following is a summary of “Spesolimab Reduces Inflammation in Generalized Pustular Psoriasis: Molecular Characterization ...

Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical ...

Cell Analysis of Debrided Diabetic Foot Ulcers Reveals Dysregulated Wound Healing Environment in Non-Hispanic Black Patients,” published in the March 2025 issue of Journal of Investigative Dermatology ...