We show here that these diverse peptide sequences bind with comparable affinities to the Numb PTB domain at a common binding site on the surface of the protein. The NMR structure of the Numb PTB ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...

The Protein and Peptide Science Group (PPSG) is one of the RSC's many Interest Groups. The Interest Groups are member driven groups which exist to benefit RSC members, and the wider chemical science ...

Their discovery of a novel mini hairpin structure in a nascent peptide that induces translation arrest sheds light on peptide-mediated regulatory mechanisms.

They consist of folded peptide chains, which in turn are made up of a series of amino acids. From stabilising cell structure ...