A plasmid is a small, circular, double-stranded DNA molecule that is distinct from a cell's chromosomal DNA. Plasmids naturally exist in bacterial cells, and they also occur in some eukaryotes.
Plasmid DNA (pDNA) is a key material for producing gene therapies, mRNA and DNA vaccines. The alkaline lysis process to isolate pDNA is simple on the benchtop, but it’s challenging at industrial scale ...
A scaleable method for the liquid-phase separation of plasmid DNA from RNA. In the course of experiments on the potential of nucleic acid compaction for enhancement of chromatographic adsorption ...
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