Protease inhibitors (PIs) block the activity of the protease enzyme ... Capsid inhibitors interfere with multiple stages of the HIV lifecycle. The HIV capsid is a cone-shaped structure that provides a ...

The title of his talk, which is open to the public, is “Structure-based Antiviral ... led by ORNL to design covalent inhibitors that target the papain-like protease (PLpro) of SARS-CoV-2 ...