But now, this exclusive club has a new member — two groups report the detailed biochemistry and structure of the Mycobacterium tuberculosis (Mtb) 20S proteasome. In a parallel collaborative ...

Reporting in Nature, Lin and colleagues show that selective inhibition of the mycobacterial proteasome with certain oxathiazol-2-one compounds might be useful in targeting this non-replicating ...

Their compounds activate 20S proteasomes, which can identify and ... and chief scientific officer Dr Diogo Feleciano stated: ...