About 100 cells divide every second in our body. A key protein in cell division is a protein kinase termed Plk1, because it ...

Researchers have unveiled a novel immune mechanism by which tandem kinases combat pathogen invasion: an atypical NLR protein, ...

Delve into the kinase inhibitors' diverse landscape, from cancer breakthroughs to autoimmune disease innovations.

The anti-melanogenesis effect of ligustroside derived from Ligustrum japonicum and its underlying mechanisms are explored.

A new study reveals that autism-like symptoms in mice emerge when two nerve proteins—MDGA2 and BDNF—fall out of balance.

A patient with HPV-positive head and neck squamous cell carcinoma was dosed in a phase 1 clinical trial evaluating APR-1051.

Protein kinase research presents an opportunity to explore molecular targets in the body to treat diseases like cancer and autoimmune disorders. These enzymes have the potential to bind to ...

This study reveals that the expression of the Src-family kinase (SFK), FGR, alone can induce cell differentiation similar to RA."BUFFALO, NY – March ...

Ideaya Biosciences (IDYA) announced that the FDA has granted breakthrough therapy designation for darovasertib, a protein kinase C inhibitor, ...

Researchers have revealed for the first time how a key protein linked to Parkinson's mutates, leads to cell death in the ...

Researchers from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences and the Shanghai Institute of Organic Chemistry have divulged EGFR (L858R/T790M/C797S triple mutant) and ...