The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

Protein structure prediction remains a very difficult ... there is an unprecedented level of enthusiasm and information exchange that will surely catalyze future advances.

Advanced physics-based computational methods and machine learning offer clear pictures of proteins and how they interact at the atomic level with ... even when a protein structure was available ...

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and ...

Scientists at the University of Iowa have made an exciting discovery that could lead to new cancer-fighting drugs. They found ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...

A study from Cornell researchers could enable a quantum leap forward in identifying and deciphering cancer-driving genetic ...

After translation, the polypeptide is finally folded into the correct shape and becomes a protein. Peptide bonds form between the adjacent amino acids to finalise the structure.