The purine structure consists of a pyrimidine ring (positions 1 to 6 ... GTP is also a substrate for the synthesis of RNA during transcription. Purine metabolism involves the synthesis and breakdown ...

Investigators led by Issam Ben-Sahra, Ph.D., associate professor of Biochemistry and Molecular Genetics, have discovered how ...

In the current study, Krainc and his collaborators sought to better understand how CHCHD2 impacts cellular metabolism in Parkinson's disease. First, investigators examined the mitochondrial ...