在这里,作者表明,利什曼原虫中不寻常的染色体大小依赖的DNA复制时间受到RNA-DNA杂交的影响,这种杂交被内切酶RNase H1识别。 探秘利什曼原虫基因组:R 环与 RNase H1 对 DNA 复制及基因组稳定性的影响 近日,来自格拉斯哥大学寄生虫学中心(The University of Glasgow ...
Using 2′-cytidylic acid as an inhibitor the active region of the molecule is found to lie in a cleft. An approximate arrangement of the polypeptide chain in the ribonuclease molecule is suggested.
Recent research has focused on dual inhibitors that can simultaneously target both the polymerase and ribonuclease H (RNase H) activities of reverse transcriptase, as well as exploring new ...
Four non-nucleoside RT inhibitors (NNRTIs ... thumb and connection subdomains) and an RNase H domain. The four subdomains and the RNase H domain are shown in blue, green, light purple, orange ...