The renin-angiotensin-aldosterone system (RAAS) is now known to play a key role in the pathogenesis of hypertension and a range of other cardiovascular diseases. Two groups of drugs, the ACE ...

physicians must be aware of clinical circumstances that may promote the development of hyperkalemia The renin–angiotensin–aldosterone system (RAAS) has a pathogenetic role in several edematous ...

Perspective from Keith C. Ferdinand, MD CHICAGO — The investigational aldosterone synthase inhibitor lorundrostat effectively lowered 24-hour BP for adults with well-treated, uncontrolled and ...

The study is evaluating the efficacy and safety of lorundrostat, a novel aldosterone synthase inhibitor ... with 25 mg of ...