New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D.

opening channels) or engage in crosstalk with the nucleus (to modulate gene transcription). Figure 3: Structural diversity of ligand shapes accommodated by steroid-hormone receptors. A further ...

Bsense Bio Therapeutics Ltd. has disclosed new potassium voltage-gated channel subfamily KQT member 2/3 (KCNQ2/3) activators and transient receptor potential cation channel subfamily V member 1 (TRPV1 ...

Their findings are published in Science Advances. Cys-loop receptors are ligand-gated ion channels with two domains connected by a short linker. The top domain is located extracellularly ...

The protein they studied is the P2X 7 receptor, an ion channel that is found throughout the body. P2X 7 is unique: once it's ...

Several clinical trials have demonstrated that AT-II-receptor antagonists are as effective as calcium-channel blockers, b-blockers, and ACE inhibitors in the treatment of hypertension and induce ...