Although several types of excitable cells exist — including neurons, muscle cells, and touch receptor cells — all of them use ion channel receptors to convert chemical or mechanical messages ...

opening channels) or engage in crosstalk with the nucleus (to modulate gene transcription). Figure 3: Structural diversity of ligand shapes accommodated by steroid-hormone receptors. A further ...

Their findings are published in Science Advances. Cys-loop receptors are ligand-gated ion channels with two domains connected by a short linker. The top domain is located extracellularly ...

New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D.

Bsense Bio Therapeutics Ltd. has disclosed new potassium voltage-gated channel subfamily KQT member 2/3 (KCNQ2/3) activators and transient receptor potential cation channel subfamily V member 1 (TRPV1 ...

Several clinical trials have demonstrated that AT-II-receptor antagonists are as effective as calcium-channel blockers, b-blockers, and ACE inhibitors in the treatment of hypertension and induce ...