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St. Jude Children’s Research Hospital scientists resolved the mystery in a new study, showing retinoic acid uses a novel mechanism to kill metastasized neuroblastoma. The drug “hijacks” a normal ...
The researchers showed that BMP signaling makes neuroblastoma cells much more vulnerable to retinoic acid. "Unexpectedly, we ...
Retinoic acid (RA) is one of several molecules that ... Given that RA and the Fgf pathway are also interrelated in other organs, it will be interesting to find out whether similar regulatory ...