近年来，RNA编辑技术因其可逆性、高精度与低免疫原性，成为基因治疗研究的热点。然而，如何实现对RNA编辑的“时空可控性”，仍是一大技术瓶颈。 2025年3月31日，华东师范大学李大力、刘明耀和杜冰团队在《Nature Biotechnology》发表题为《Engineering a photoactivatable A-to-I RNA base editor for gene therapy i ...

The central dogma of molecular biology suggests that the primary role of RNA is to convert the information stored in DNA into proteins. In reality, there is much more to the RNA story. However ...

Messenger RNA (mRNA) is a subtype of RNA. An mRNA molecule carries a portion of the DNA code to other parts of the cell for processing. mRNA is created during transcription. During the ...