[26] In addition, some of the changes in circulating marker levels may be a consequence of silent plaque rupture and/or subsequent healing. Detection of vulnerable or rupture-prone lesions is of ...

During the progression of atherosclerosis, development of plaques is initiated by the arterial accumulation and oxidation of low-density lipoproteins (LDLs). This initiates an inflammatory process ...

The final stage of atheroma progression is characterized by a large necrotic core and low SMC density, with a correspondingly thin fibrous cap — a vulnerable plaque prone to rupture and thrombosis.

The 'vulnerable' plaque is a term which describes a plaque that is destabilized and thus prone to induce atherosclerotic cardiovascular events. The determination of biomarkers related to ...