Further work 6 showed that the treatment of lymphoid progenitor cells with IL-3 resulted in the phosphorylation of BAD at two sites, serine residues 112 and 136 (this numbering is based on the ...

Protein phosphorylation is a covalent post-translational modification event that is essential for regulation and maintenance of most biological processes in eukaryotes 1. Conventionally ...

New serine biomarkers show promise for early Alzheimer's detection, linking tau assemblies to cognitive decline and offering ...

Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...

Researchers say CSF biomarker test correlates with the severity of cognitive decline, independent of other factors, including brain amyloid deposition.

The emergence of pseudokinases and pseudophosphatases has made phosphorylation cascades even more complicated. My lab focuses on various functional characteristics of the pseudophosphatase map kinase ...

In the PamStation®12 system, active kinases within a cellular/tissue lysate will phosphorylate specific peptide substrates within the microarray which survey the particular kinome (tyrosine or ...