These models can be very pertinent for evaluating the effects of HbF modulation on the pathophysiology of the sickle cell disease phenotype and for providing a quantitative basis for the ...

Can we predict that natural selection will weed out genetic disease over time? Sickle-cell trait haplotype distribution shows the genetic advantages of this mutation. In the deoxygenated ...

A Fayetteville teen is making history in North Carolina after undergoing a new gene therapy for sickle cell disease. Aaron Scott was diagnosed with sickle cell at birth. Sickle cell is a genetic ...

"This causes a metabolic phenotype that resembles a glutamine ... L-glutamine is also used to alleviate symptoms of sickle cell disease, but how this drug works has similarly been contentious.

TOPEKA, Kan. (WIBW) - About 100,000 people in the U.S. are living with sickle cell disease. Most of them are of African descent. A blood drive Saturday aims to fill a need for those patients.

Children with sickle cell disease, a chronic hemolytic anemia, present with a wide variety of neurological syndromes, including ischemic and hemorrhagic stroke, transient ischemic attacks ...