Now, Hattersley et al. describe the response to sulfonylurea therapy in patients with SUR1 mutations. The study observed 27 patients with SUR1 diabetes after attempted transfer to sulfonylurea ...

450_{\\text{SU}1}$-mediated N-dealkylation of the sulfonylurea 2-methylethyl-2,3-dihydro-N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-1, 2-benzoisothiazole-7-sulfonamide-1,1-dioxide (R7402).

Adjunct to diet and exercise in type 2 diabetes, as initial therapy or as second-line therapy when response to a sulfonylurea or metformin is inadequate. Take with meals. First-line: initially 2 ...