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sulfonylurea receptor 1 and Kir6.2 (the two components of the ATP-dependent potassium channel), glutamate dehydrogenase, glucokinase, and short chain 3-hydroxyacyl-CoA dehydrogenase ATP-dependent ...
Of note, lower sulfonylurea doses were needed to treat the patients with SUR1 mutations after transfer than had been reported for those with Kir6.2 mutations (0.26 versus 0.45 mg/kg daily ...
Am J Health Syst Pharm. 2006;63(10):929-938. The goal of sulfonylurea overdose management is the return of euglycemia, with either dextrose supplementation or reduction of insulin secretion.
In patients with type 2 diabetes, the risk for chronic kidney disease differed among users of SGLT2 inhibitors, GLP-1 receptor agonists, DPP-4 inhibitors, and sulfonylurea.
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