Our approach to super-resolution microscopy is fundamentally different from most existing techniques such as stimulated emission depletion microscopy, structured illumination microscopy, or ...

Stochastic Optical Reconstruction Microscopy (STORM) reconstructs a super-resolution fluorescence image by combining precise localization information for individual fluorophores in complex fluorescent ...

Another challenge is the need for specialized fluorescent probes and labeling strategies that are compatible with super-resolution imaging. The development of brighter, more photostable, and ...

Helped by fluorescent molecules the Nobel Laureates in Chemistry 2014 ingeniously circumvented this limitation. Their groundbreaking work has brought optical microscopy into the nanodimension.

Researchers are exploring the use of adaptive optics to correct for aberrations in thick samples, as well as the integration of STED with other super-resolution techniques like single-molecule ...

Structured illumination microscopy is one of the super-resolution ... for background-free super-resolution imaging. While some previous methods utilized random fluorescence emission from single ...

and super-resolution fluorescence imaging systems. The facility also includes an analysis suite with computers that have licensed image analysis programs installed. Use of the Brandeis Light ...

A powerful new technique combines expansion microscopy with lattice light-sheet microscopy for nanoscale imaging of fly and mouse neuronal circuits and their molecular constituents that’s roughly ...

AI transforms label-free photoacoustic microscopy into confocal microscopy. ScienceDaily . Retrieved February 11, 2025 from www.sciencedaily.com / releases / 2025 / 01 / 250117112320.htm ...

The Purdue Imaging Facility (PIF) is a research resource for Purdue faculty/staff/students and other academics and non-academics who want access to state-of-the-art ...