Vahedi and colleagues review the mechanisms shaping the epigenetic landscape of CD4 + and CD8 + T cells during development and differentiation.

研究表明，在实验室测试和动物模型中，靶向EphA3的car-T细胞都能有效地寻找并消灭胶质瘤细胞。 近年来，car-T免疫疗法除了被用来治疗急性白血病和 ...

Immunostimulant therapy using agonistic cytokines or activating antibodies has been associated with off-target side effects, failure to preferentially activate cytotoxic lymphocytes (CTLs) over ...