However, since TNF is a cytokine with pleiotropic effects, interfering with many immunological functions and pathways, the precise mechanisms by which these agents reduce inflammation in these ...

Tumor necrosis factor (TNF)-alpha, a proinflammatory cytokine, has been implicated in the pathogenesis of AD. Objective: To investigate the use of a biologic TNF-alpha inhibitor, etanercept was ...

After a computational search for miRNAs that bind to the 3′ UTR of TNF alpha, the authors experimentally ... Vasudevan is interested in the mechanism behind this process. She says, “I want ...

It has been found to regulate macrophage activity and reduce the expression of pro-inflammatory cytokines like tumor necrosis factor-alpha (TNF-α), which plays a significant role in the ...

today announced that it has achieved a key safety data milestone supporting expanded and longer-term clinical studies of its novel TNF-alpha (TNF-α) inhibitor drug, isomyosamine, in multiple ...