In the REFLEX trial, patients who had an inadequate response to TNF antagonists and who were on weekly MTX with mean disease duration of 12 years were studied. [18] They were randomized to receive ...

Background: To analyse available evidence on the efficacy and safety of anti-TNFα drugs (infliximab, etanercept and adalimumab) for treating rheumatoid arthritis (RA). Methods: We searched ...

Science Progress (1933-), Vol. 104, No. 2 (2021), pp. 1-10 (10 pages) No consistent results have been reached on the relationship of interleukin-1 (IL-1) rs1800587 polymorphism with the susceptibility ...

“In patients with rheumatoid arthritis, glucocorticoid therapy is associated with higher mortality.” The lack of a significant negative impact on cancer outcomes from TNF inhibitors is ...