为探究 tau 蛋白异常折叠和聚集机制，研究人员运用拓扑和几何方法分析 tau 蛋白结构，发现相关位点和能量变化，为疾病治疗提供方向。

Biogen Inc. (Nasdaq: BIIB) today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track ...

Delve into how the biotech industry is pivoting from the amyloid hypothesis to find new Alzheimer's disease treatments.

W ith two new treatments for Alzheimer’s disease approved in recent years, there’s growing hope for people at risk of the ...

Scientists have developed a blood test for Alzheimer’s disease that can help diagnose the neurodegenerative disease while ...

A new blood test test could determine how far Alzheimer's has progressed and could also help confirm whether another ...

A recent study revealed that an experimental blood test for Alzheimer’s disease not only can help in accurate diagnosis but ...

BIIB080 is an antisense oligonucleotide therapy designed to target microtubule-associated protein tau mRNA and reduce the production of tau.

The new test could help identify which patients are most likely to benefit from new Alzheimer’s drugs. A newly developed ...

A new blood test for Alzheimer’s disease not only helps diagnose the condition, but it may also indicate how far it’s progressed. The test measures levels of a specific protein (MTBR-tau243) linked to ...

It wasn't that long ago that the only way to test for Alzheimer's disease was to perform an autopsy on someone who had been ...

Figure 5: Age-dependent increase in insoluble tau in P301L (JNPL3) mouse brains. We have reported a transgenic mouse line, JNPL3, expressing human tau with the P301L mutation that develops NFT ...