Various immune pathways in the host, such as TH1, TH2, TH3, TH9, TH17, TH22, TH1-like, and THαβ, have been identified. While TH2 and TH9 responses primarily target multicellular parasites ...

1 Th1 cells primarily produce interferon (IFN)-g and interleukin (IL)-2, whereas Th2 cells produce IL-4, IL-5, IL-6, IL-10, and IL-13. The two helper T cell classes also differ by the type of immune ...

Helper T cells in the body, which help protect against infections but also become hyperactive in autoimmune diseases or allergies, can be grouped into three classes: they are TH1, TH2 and TH17 cells.

Soquelitinib has been shown to affect T cell differentiation and induce the generation of Th1 helper cells while blocking the development of both Th2 and Th17 cells and production of their secreted ...

In conclusion, Tim-3 was characterized as a novel immune checkpoint molecule with pathophysiological significance in respiratory oncology. Its stage-dependent expression dynamics and multimodal ...