Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

Rheumatoid arthritis (RA) is a complex disease in which environmental agents are thought to interact with genetic factors that influence susceptibility. This interaction triggers immunologic ...

However, DcR3 might also contribute to the pathogenesis of RA by downregulating the apoptotic pathways of inflammatory cells, which are mediated by Fas ligand. In fact, defective clearance of ...

To gain a clearer understanding of CII's role in the pathogenesis of RA, researchers at Queen Mary, University of London and others studied its behavior within an inflamed joint, when modified by ...

is there a linkage of the interleukin-1 (IL-1), IL-10 or IL-4 genes to RA? Clin Exp Rheumatol 2001; 19: 709–714. 21. Giannini D, Antonucci M, Petrelli F, et al. One year in review 2020: pathogenesis ...

Patients with rheumatoid arthritis are associated with an increased risk for heart failure, particularly heart failure with preserved ejection fraction.

Recent research explores how gut microbiome imbalances contribute to rheumatoid arthritis, and how dietary interventions could be key to reducing inflammation and improving patient outcomes.