The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.

He had a prior history of coronary heart disease, high-grade ischemic cardiomyopathy, chronic renal failure, and chronic gouty arthritis with multiple gouty tophi. He had also had hyperuricemia ...

Creatinine clearance was the major factor independently associated with early presentation with tophi. Although other factors such as diuretic use and older age were associated with presence of ...