Topiramate, an antiepileptic drug with potential mechanisms of action including sodium channel blockade, inhibition of glutamate receptors, and enhancement of γ-aminobutyric acid (GABA ...

Its various modes of action help to improve neural inhibition and lessen neuronal excitement. Because of its many different processes, topiramate causes a number of off-label effects in people who ...

To evaluate the efficacy and tolerability of topiramate in children with epilepsy younger than 2 years of age, we retrospectively reviewed the records of patients treated at our institution ...