This active repressor can bind to a region near the promoter called an operator (yellow) and thus interfere with RNA polymerase binding to the promoter, effectively preventing transcription.

Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...

"This surprising discovery points to a small but crucial feature of the transcription factors: their START domain," a lipid-binding region within the TFs, which the researchers liken to a foreman ...

This precise transcribing of genes is handled by proteins known as transcription factors, which bind to the regulatory DNA, thereby generating instructions for the coding region. A fly's body has ...

The lab of Dr. Mark Magnuson, Louise B. McGavock Professor and professor of molecular physiology and biophysics at Vanderbilt ...