Most neurons receive thousands of synaptic inputs onto widely spread dendrites. Because of dendritic filtering, distant synapses should have less efficacy than proximal ones. To investigate this ...

Thus, the truth may be a mixture of these two possibilities ... How do neurons manage to become self-organized, accurately balancing protein removal from synapses and trafficking into synapses ...

In research published in Cell Reports, Harnett and his team show how individual neurons can contribute to both parts of this ...

They are the most common neuron found in mammalian bodies. Neuron Function Synapses Neural synapses are junctions between neurons that permit neural communication. Synapses come in two different forms ...

namely sensory neurons from the siphon that connect to motor neurons in the gill. In a dish, Martin cultured a single sensory neuron with a bifurcated axon that formed synapses with two separate motor ...

There, they begin to form connections with other neurons. The process of forming these connections, or synapses, is called synaptogenesis. It occurs rapidly in the months before and after birth ...

Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent continuous stimulation of postsynaptic neurons. There are two types of removal: Re-uptake – the ...

Specifically, Toll receptor signaling controls Draper/MEGF10/Jedi-1 receptor expression to regulate glial engulfment of dying neurons during development. We extended this work and found that Draper is ...

Chemical synapses are biological junctions through which neurons' signals can be sent to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to ...

Our research is focused on molecular and supramolecular structures that facilitate communication between neurons at the chemical synapse and how such structures are perturbed in neurological disease.