"The interferon pathway [mediated by this antiviral protein produced by leukocytes ... Dengue is caused by four viral serotypes (DENV-1 through DENV-4) and, when symptomatic, progresses through ...

When they detect the presence of RNA viruses, they activate interferons through the mitochondrial antiviral signaling (MAVS) pathway. The MAVS protein resides on the outer membrane of a cell's ...