Whereas, Paget disease involves thickened and weaker-than-normal bone. The cause is not clear, but some studies suggest that it could be due to genetics and environmental factors. Both the ...

Paget’s disease of the vulva is a rare type of skin disease that develops on the vulva. It is very slow to spread and is typically found in women who have been through menopause. In some cases, ...

Linkage analysis was originally used to identify familial Paget disease genes. One study indicated that about 29% of families with a history of Paget disease have a mutation in the sequestosome 1 ...

The disease seems to occur in one of two patterns: monostotic (localized) and polyostotic (generalized). In humans, the most commonly affected bones are the pelvis, skull, femur, spine ...

Ipriflavone can block part of the process that leads to bone loss. A bone disease that can cause pain (Paget disease). Early research shows that taking ipriflavone might decrease bone pain in some ...