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In a collaborative high-throughput effort to determine the three-dimensional structures of small proteins, two studies demonstrate that X-ray crystallography and nuclear magnetic resonance (NMR ...
There, as Vice President of Structural Biology, he played a substantial role in the transition of the company from one based on its platform technology — high-throughput X-ray crystallography ...
X-Ray Crystallography The new knowledge of the atomic structure of matter uncovered over the past half-century by the X-ray-diffraction technique has led to a fundamental revision of ideas in many ...
Modern biological sciences are enriched by the revolution in structural biology. Advances in techniques such as electron microscopy (EM), X-ray crystallography and NMR, coupled with modern biophysical ...
The crystallisation equipment provided by the facility allows researchers to prepare a variety of samples for X-ray diffraction. Methods available at the facility include: custom crystallisation ...
X-ray scattering, particularly SAXS, is extensively used in structural biology to study the shape, size, and interactions of biological macromolecules like proteins, nucleic acids, and lipid membranes ...
All of the single crystal diffractometers are equipped with modern kappa-geometry goniometers. Two of these have conventional fixed Mo-anode X-ray tubes and are used for routine samples. The third is ...
Jon Mason and Miles Congreve from Heptares will describe what protein-ligand X-ray data can do for your medicinal chemistry project. How these data can be interpreted and used to influence both the ...
The Biomolecular X-ray Crystallography Core (BioX) within the Department of Biochemistry offers extensive resources for the crystallisation and structural determination of biological macromolecules ...
Our group applies structural (cryo-EM, x-ray crystallography and NMR), biochemical and biophysical methods together with functional studies to investigate macromolecular-mediated recognition, ...
Imaging technologies like cryo-electron microscopy and X-ray crystallography help researchers ... "But the future of structural biology is going to be in looking at the mechanics, or the dynamics ...
In our studies we use integrated computational, biochemical and structural methods including X-ray crystallography, NMR spectroscopy and Cryo-electron microscopy ... We are also interested in ...
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