Leveraging the power of nature for sustainable chemical synthesis, utilizing enzymes ... Claisen-like condensation of amino acids with an acyl-CoA thioester to generate α-aminoketones, however ...

(a) In the previously known pathway found in E. coli and related bacteria, PlsB catalyzes the formation of lysophosphatidic acid (lyso-PA) from glycerol 3-phosphate (G3P) and acyl-ACP (or acyl-CoA ...