点击蓝字关注我们【导读】脑转移是表皮生长因子受体(epidermal growth factor receptor, ...
近年来,随着分子肿瘤学的飞速发展,越来越多的研究揭示了遗传因素在肺癌发病机制中的重要作用。其中,表皮生长因子受体(Epidermal Growth Factor Receptor,EGFR)基因的突变成为了研究的热点。EGFR 突变不仅与 NSCLC 的发生发展密切相关,还影响着患者对靶向治疗 ...
EGFR 20 外显子插入(EGFR ex20ins)突变是非小细胞肺癌(NSCLC)中除 EGFR 19 外显子缺失(19-Del)和 21 外显子 L858R 点突变(21-L858R)两大常见突变外的 EGFR 第三大突变,占所有 NSCLC ...
在阻断增殖信号的研究中,受体酪氨酸激酶(Receptor Tyrosine Kinase,RTK)抑制剂是常用的手段之一。RTKs 家族庞大,包括 EGFR、PDGFR、IGFR、VEGFR 等,它们就像细胞表面的 “信号指挥官”,与生长因子结合后能激活一系列促进癌症进展的信号级联反应。众多 RTK 抑制剂 ...
EGFR is short for epidermal growth factor receptor. It’s a protein that helps cells grow, and it’s found in both healthy cells and cancer cells. A mutation in this gene can cause cells to ...
“EGFR” stands for “epidermal growth factor receptor.” The EGFR gene controls the production of EGFR proteins, which are found in both healthy and abnormal cells. They help cells grow and divid ...
NT219 in combination with EGFR antibody cetuximab (Erbitux) is currently entering a Phase 2 study for head and neck cancer REHOVOT, Israel, March ...
Hoth Therapeutics, Inc. (NASDAQ: HOTH), a clinical-stage biopharmaceutical company dedicated to developing innovative therapies, today announced its intention to submit an Expanded Access application ...
First clinical data demonstrating robust confirmed responses and CNS anti-tumor activity for firmonertinib in first-line NSCLC EGFR PACC ...
6 个月on MSN
epidermal growth factor receptor (EGFR) wildtype (WT), locally advanced/metastatic nonsquamous non-small cell lung cancer ...
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