EGFR is short for epidermal growth factor receptor. It’s a protein that helps cells grow, and it’s found in both healthy cells and cancer cells. A mutation in this gene can cause cells to ...

“EGFR” stands for “epidermal growth factor receptor.” The EGFR gene controls the production of EGFR proteins, which are found in both healthy and abnormal cells. They help cells grow and divid ...

Why then would most of the crystallized forms of EGFR show the receptor in its active conformation? Most likely, the crystallization process necessary for analyzing protein structure caused a high ...

NT219 in combination with EGFR antibody cetuximab (Erbitux) is currently entering a Phase 2 study for head and neck cancer REHOVOT, Israel, March ...

epidermal growth factor receptor (EGFR) wildtype (WT), locally advanced/metastatic nonsquamous non-small cell lung cancer ...

has been designed to expand the therapeutic index and minimise toxicities by avoiding off-target inhibition of epidermal growth factor receptor (EGFR). The multicentre, open-label, dose escalation ...

The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?

First clinical data demonstrating robust confirmed responses and CNS anti-tumor activity for firmonertinib in first-line NSCLC EGFR PACC ...

Hoth Therapeutics, Inc. (NASDAQ: HOTH), a clinical-stage biopharmaceutical company dedicated to developing innovative therapies, today announced its intention to submit an Expanded Access application ...

Ovarian cancer (OC), the most lethal gynecological malignancy, is the fifth leading cause of cancer-related death in women. Despite advances in treatment, the primary challenges in overcoming ovarian ...

2024;42(3):3593-3605. 2 ClinicalTrials.gov. A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor ...

HT-001 is being developed to alleviate the adverse dermatological effects experienced by cancer patients undergoing epidermal growth factor receptor (EGFR) inhibitor ...