University of Iowa, The Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA Objective: The objective of the Predict-HD study is to use genetic, neurobiological and refined clinical ...

As a chronic progressive disease, Parkinson's disease (PD) has a presymptomatic interval; that is, a period during which the pathological process has begun, but motor signs required for the clinical ...

Correspondence to Dr Dearbhla Kelly, Centre for the Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford OX3 9DU, UK; ...

Department of Neurology, The Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, UK Correspondence to: Dr M Hadjivassiliou, Department of Neurology, The Royal Hallamshire Hospital, Glossop ...

OBJECTIVES Neuropsychological investigations have shown a degree of cognitive dysfunction in a proportion of non-demented patients with ALS. Respiratory muscle weakness in ALS can lead to nocturnal ...

Objectives We aimed to compare the long-term outcomes and surgical benefits between moyamoya disease (MMD) and atherosclerosis-associated moyamoya vasculopathy (AS-MMV) using high-resolution MRI ...

Movement disorders arise from the complex interplay of multiple changes to neural circuits. Successful treatments for these disorders could interact with these complex changes in myriad ways, and as a ...

Correspondence to Dr Timothy Rittman, Department of Clinical Neurosciences, University of Cambridge, Herchel Smith Building, Forvie Site, Addenbrooke's Hospital Site, Robinson Way, Cambridge CB2 0SZ, ...

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder affecting the upper and lower motor neurons. A key clinical feature of ALS is the absence of accurate, early-stage ...

3 Department of Endocrinology, University Hospital “Marqués de Valdecilla” (IFIMAV), University of Cantabria, Santander, Spain Correspondence to Dr Javier Riancho, Service of Neurology, University ...

Correspondence to: Dr C E Clarke, Department of Neurology, City Hospital, Dudley Road, Birmingham B18 7QH, UK; c.e.clarke{at}bham.ac.uk ...